Iodine is one of the most widely used elements both domestically and industrially. A French physician was the person to ever use lugols iodine solution in the year 1829. He prepared it by mixing elemental iodine with potassium iodide and dissolving in water. Today, the resultant compound is widely used in domestic and industrial application. Its use has been especially appreciated in scientific research. It is also known by other terms such as Markodine, iodine potassium iodide and Strong solution.
For topical use such as in the case of minor wounds on the skin there are several formulations available. The main types used include ointment, gel or tincture. Commonly, these formulations are mixed with another ingredient known as povidone which serves to increase the effectiveness. The tincture is also said to be effective in emergency disinfection of water. The mechanism of action is not clear in this case.
In biochemistry, Markodine is used in detection of starch in some organic compounds. In the presence of starch there will be a blue black colour change. This is because the element interacts with the polysaccharides found in starch. It, however, does not detect simple sugars such as glucose, fructose and galactose. A similar pattern of staining is seen when testing for a condition known as amyloidosis although amyloid is actually protein and not starch.
The solution is widely used in cervical cancer screening. In this test, it is applied on the vaginal wall and on the cervix under the exposure of an instrument known as a colposcope. Since normal vaginal and cervical tissues have a high amount of glycogen, they will stain brown. Abnormal or suspicious tissues do not stain adequately and appear paler. It is the light staining areas that are used to provide biopsy specimens for histological examination.
Patients suffering from Graves disease, a severe form of hyperthyroidism, may benefit from a small dose of the compound when undergoing surgery. It has been suggested by some experts that the compound may reduce blood loss associated with thyroidectomy. This effect is not seen in patients that have euthyroid hormone levels or in those on antithyroid medication.
One of the earliest uses of the solution was the treatment of gout. With the discovery of better drugs, it has been dropped from the list of the commonly used drugs for the condition. The same trend has been witnessed in the treatment of hyperthyroidism. In the latter case, it has fallen out of favour due to its ability to inhibit thyroid hormone synthesis. This is termed the Wolff Chaikoff phenomenon.
Macroalgae require elemental iodine for growth and survival. The element is also important for other coral reef inhabitants. For these reasons, it is heavily used in the maintenance of marine ecosystems. Its effects are mainly due to its ability to significantly reduce the number of harmful bacteria and parasites. The other major benefits are the prevention of coral reef bleaching and polyp expansion.
When used in excess, the compound may have some unwanted effects on the body. At low dilutions, it is said to have an irritating and corrosive effect on the stomach mucosa. This may be encountered when conducting endoscopic examinations. Generally, however, it is regarded as being safe.
For topical use such as in the case of minor wounds on the skin there are several formulations available. The main types used include ointment, gel or tincture. Commonly, these formulations are mixed with another ingredient known as povidone which serves to increase the effectiveness. The tincture is also said to be effective in emergency disinfection of water. The mechanism of action is not clear in this case.
In biochemistry, Markodine is used in detection of starch in some organic compounds. In the presence of starch there will be a blue black colour change. This is because the element interacts with the polysaccharides found in starch. It, however, does not detect simple sugars such as glucose, fructose and galactose. A similar pattern of staining is seen when testing for a condition known as amyloidosis although amyloid is actually protein and not starch.
The solution is widely used in cervical cancer screening. In this test, it is applied on the vaginal wall and on the cervix under the exposure of an instrument known as a colposcope. Since normal vaginal and cervical tissues have a high amount of glycogen, they will stain brown. Abnormal or suspicious tissues do not stain adequately and appear paler. It is the light staining areas that are used to provide biopsy specimens for histological examination.
Patients suffering from Graves disease, a severe form of hyperthyroidism, may benefit from a small dose of the compound when undergoing surgery. It has been suggested by some experts that the compound may reduce blood loss associated with thyroidectomy. This effect is not seen in patients that have euthyroid hormone levels or in those on antithyroid medication.
One of the earliest uses of the solution was the treatment of gout. With the discovery of better drugs, it has been dropped from the list of the commonly used drugs for the condition. The same trend has been witnessed in the treatment of hyperthyroidism. In the latter case, it has fallen out of favour due to its ability to inhibit thyroid hormone synthesis. This is termed the Wolff Chaikoff phenomenon.
Macroalgae require elemental iodine for growth and survival. The element is also important for other coral reef inhabitants. For these reasons, it is heavily used in the maintenance of marine ecosystems. Its effects are mainly due to its ability to significantly reduce the number of harmful bacteria and parasites. The other major benefits are the prevention of coral reef bleaching and polyp expansion.
When used in excess, the compound may have some unwanted effects on the body. At low dilutions, it is said to have an irritating and corrosive effect on the stomach mucosa. This may be encountered when conducting endoscopic examinations. Generally, however, it is regarded as being safe.
About the Author:
Make sure you check out the following homepage to find out about lugols iodine solution. Feel free to visit this website on http://iodineforlife.com right now!
No comments :
Post a Comment