What The Liposomal Encapsulation Means To Clinical Therapy

By Kristen Baird


The use of liposome in clinical medicine first came to trial in the 1960s, and research and clinical trials that have since followed made sure that this amazing technological evolution can now be applied for both clinical therapy and in other aspect of life. However, the liposomal encapsulation technology (LET) is still in its early stages of development, with little information known to the wider public.

Many scientists, researchers and industrialist alike agree that this technology is likely to revolutionize the oral pharmacological therapy and may soon be in realm of use by any common man. Currently, it provides a safer and a unique way of treating the racehorse without having to use the syringes and needles.

In this technology, phospholipid membrane (liposome) is used to encase a prescribed amount of pharmaceutical compounds with the aim of preventing their degradation as they pass through the gastrointestinal tract. This option offers an excellent transfer mechanism that is not available with other drug administration methods. The method is now used in other fields other than in clinical therapies. These include supplement manufacturers, topical moisturizers and the beauty product manufacturers among others.

Phospholipid liposome is used come up with a defense that is capable of repelling the negative impacts that can result from the body radicals, digestive juices, the alkaline solutions, and even salts. Since the protection only lasts when the compounds are on the way to their target to the moment they reach the targeted tissue, the cells in the targeted tissue immediately allows the compound in and transfers the same into the intracellular space making the method so effective.

The effectiveness of this technology relies on the fact that liposomes easily penetrate cell walls and many other infectious biofilms, which allows for a highly effective delivery system against these pathological infections. Research has found that 5 grams of Vitamin C encased in liposomes is as effective as 50 grams of Vitamin C that is delivered intravenously demonstrating how effective this technology is in terms of delivery of compounds to the targeted tissues.

Clearly, the advantages of LET over the other forms of drug delivery are many. It allows nutrients to transport power packed natural compounds to the targeted tissues and organs without discomposing the same. This makes a lot of medical and economic sense. Normally, the drugs would be affected by a number of environmental factors as they pass to the tissues. These include oxygen, moisture, differing pH, and enzymes among others. This in addition to factors that affect absorption of nutrients into the body, such as fillers, sugars, binders, and sugar can cause a problem due to incomplete absorption.

The use of phospholipids also comes with numerous benefits to the body. It cuts down on serum lipids, decreases platelet aggregation, bad cholesterol, triglyceride, and increases good cholesterol, and the fluidity of red blood cells gets amplified. In addition to these, it helps boost immunity, improves quality of memory, protects the liver and improves the ability of the body to endure exercise.

Even though the LET promises to be the most effective method of drug delivery, the old age methods such as capsules, tablets, powder forms and needles must still remain in use. These methods do not disrupt the blood flow in the system which is essential for physical fitness. Ideally, a comprehensive method that considers all the available methods would be better for any clinical therapy.




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